Author: Rachel Gonzalez Serotonin Syndrome Serotonin syndrome is a toxicity caused by increased serotonergic activity in the CNS. Common presentations include mental status changes, autonomic hyperactivity, and neuromuscular abnormalities. Causes… read more →
Author: Rachel Gonzalez In patients with a CrCl <30 mL/min, the half-life of metformin is prolonged and clearance of metformin is decreased. This can lead to lactic acidosis which… read more →
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) by Melissa Charbonneau Background: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a drug-induced idiosyncratic hypersensitivity reaction that occurs approximately 2-8… read more →
In 2008, the FDA first released a Black Box Warning for tendon rupture associated with the fluoroquinolone use. Currently marketed fluoroquinolones in the United States are: ciprofloxacin (Cipro), moxifloxacin (Avelox),… read more →
